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There are several co-factors required to make the most commonly used serotonin supplements do their job.Conversely, there are times when these supplements can react adversely with medications or other serotonin supplements, and you need to know about those, too.Elsewhere in Europe, it’s available as a prescription drug (8).

Look either for serotonin boosting supplements that contain these along with the main active ingredients or add them separately with a high-quality multivitamin mineral supplement.

SAM-e (s-adenosyl methionine): SAM-e naturally occurs in every cell of the body and brain and fuels over 100 metabolic reactions. In Europe, SAM-e is used as a prescription medication for depression, liver disease, and osteoarthritis (11).

SAM-e supplements are synthetically derived and sold in the U. Several studies show that SAM-e works as well for depression as some anti-depression medications by increasing serotonin, dopamine, and other “feel good” brain chemicals (12, 13).

All of the B vitamins are needed for a healthy, functioning nervous system and several are needed to synthesize serotonin (16).

Here are a few that are integrally connected to serotonin production.

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If this is your situation, here are some serotonin supplements proven to help increase serotonin levels naturally.

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